发明名称 PYRIDYL NON-AROMATIC NITROGENATED HETEROCYCLIC-1-CARBOXYLATE ESTER DERIVATIVE
摘要 <p>To provide a compound which can be used for the treatment of a disease associated with a fatty acid amide hydrolase (FAAH), particularly pollakiuria/incontinence of urine, overactive bladder and/or pain. [MEANS FOR SOLVING PROBLEMS] It is found that a novel pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative and a pharmaceutically acceptable salt thereof have a potent FAAH inhibitory activity. The derivative is superior in increasing the effective bladder capacity and in improving pollakiuria and has an anti-allodynic effect. Therefore, this compound can be used for the treatment of pollakiuria/incontinence of urine, overactive bladder and/or pain.</p>
申请公布号 KR20090077855(A) 申请公布日期 2009.07.15
申请号 KR20097011569 申请日期 2006.02.16
申请人 ASTELLAS PHARMA INC. 发明人 ISHII TAKAHIRO;SUGANE TAKASHI;MAEDA JUN;NARAZAKI FUMIE;KAKEFUDA AKIO;SATO KENTARO;TAKAHASHI TATSUHISA;KANAYAMA TAKATOSHI;SAITOH CHIKASHI;SUZUKI JOTARO;KANAI CHISATO
分类号 C07D401/12;A61K31/4545;C07D401/14;C07D405/14 主分类号 C07D401/12
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