发明名称 |
Methods of increasing delivery of active agents to brain comprising administering receptor associated protein (RAP) fragments conjugated to active agents |
摘要 |
This invention provides compounds of conjugates of therapeutic or active agents with RAP or a RAP polypeptide, their pharmaceutical compositions and methods for using the such compounds and compositions in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly diseases of the central nervous system or lysosomal storage diseases.
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申请公布号 |
US7560431(B2) |
申请公布日期 |
2009.07.14 |
申请号 |
US20050202566 |
申请日期 |
2005.08.12 |
申请人 |
RAPTOR PHARMACEUTICAL INC. |
发明人 |
ZANKEL TODD;STARR CHRISTOPHER M.;GABATHULER REINHARD |
分类号 |
A61K38/18;A61K38/17;A61K39/395;A61K48/00;C07K14/435;C07K14/48;C07K14/485;C07K14/50;C07K14/705;C07K19/00 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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