发明名称 |
Method for separation and enrichment of phosphopeptides |
摘要 |
The present invention relates to phosphopeptide isolation and enrichment, particularly to a highly selective and specific phosphopeptide enrichment method. The method mentioned in the invention is based on the strong interaction between zirconium phosphonate and phosphopeptide. Zirconium phosphonate is immobilized on the surface of matrix for phosphopeptide enrichment. Zirconium phosphonate could be immobilized on chip surface, it can also be immobilized on chromatographic matrix for isolation and purification of phosphopeptides. The method shows high specificity for phosphopeptides, it can be applied to purify and enrich low abundance phosphopeptide from biological samples.
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申请公布号 |
US7560030(B2) |
申请公布日期 |
2009.07.14 |
申请号 |
US20070772370 |
申请日期 |
2007.07.02 |
申请人 |
DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES |
发明人 |
ZOU HANFA;ZHOU HOUJIANG;YE MINGLIANG;FENG SHUN |
分类号 |
B01D15/08 |
主分类号 |
B01D15/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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