| 发明名称 |
Tyrosine kinase inhibitors |
| 摘要 |
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a sulfonyl indole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
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| 申请公布号 |
US7560546(B2) |
申请公布日期 |
2009.07.14 |
| 申请号 |
US20050523285 |
申请日期 |
2005.02.03 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DINSMORE CHRISTOPHER J.;BESHORE DOUGLAS C.;BERGMAN JEFFREY M.;LINDSLEY CRAIG W. |
| 分类号 |
A01N55/02;C07D487/10;A01N43/40;A01N43/62;A61K31/138;A61K31/337;A61K31/40;A61K31/404;A61K31/407;A61K31/438;A61K31/44;A61K31/4465;A61K31/4535;A61K31/454;A61K31/4545;A61K31/495;A61K31/496;A61K31/535;A61K31/5377;A61K31/54;A61K31/541;A61K31/547;A61K31/55;A61K31/551;A61K31/553;A61K39/395;A61K45/00;A61P1/04;A61P3/10;A61P27/02;A61P35/00;A61P37/02;A61P43/00;C07D;C07D209/02;C07D209/42;C07D209/96;C07D211/02;C07D215/02;C07D265/30;C07D267/02;C07D401/04;C07D401/12;C07D401/14;C07D403/02;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D413/00;C07D413/02;C07D413/04;C07D413/12;C07D413/14;C07D415/00;C07D417/04;C07D417/12;C07D417/14;C07D451/02;C07D491/04;C07D491/048;C07D491/08;C07D491/10;C07D491/107;C07D491/12;C07D498/04;C07D513/04;C07D513/08 |
主分类号 |
A01N55/02 |
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