| 发明名称 |
Compounds and methods of use |
| 摘要 |
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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| 申请公布号 |
US2009176774(A1) |
申请公布日期 |
2009.07.09 |
| 申请号 |
US20080157303 |
申请日期 |
2008.06.09 |
| 申请人 |
AMGEN INC. |
发明人 |
POTASHMAN MICHELE;KIM TAE-SEONG;BELLON STEVEN;BOOKER SHON;CHENG YUAN;KIM JOSEPH L.;TASKER ANDREW;XI NING;XU SHIMIN;HARMANGE JEAN-CHRISTOPHE;BORG GEORGE;WEISS MATTHEW;HODOUS BRIAN L.;GRACEFFA RUSSELL;BUCKNER WILLIAM H.;MASSE CRAIG E.;CHOQUETTE DEBORAH;MARTIN MATTHEW W.;GERMAIN JULIE;DIPIETRO LUCIAN V.;CHAFFEE STUART C.;NUNES JOSEPH J.;BUCHANAN JOHN L.;MCGOWAN DAVID C.;WHITTINGTON DOUGLAS A.;HABGOOD GREGORY J.;PATEL VINOD F.;LA DANIEL |
| 分类号 |
A61K31/536;A61K31/4709;A61K31/498;A61K31/502;A61K31/517;C07D213/64;C07D213/81;C07D215/22;C07D215/233;C07D215/38;C07D215/48;C07D215/54;C07D217/24;C07D237/34;C07D239/30;C07D239/34;C07D239/46;C07D239/84;C07D239/94;C07D401/12;C07D403/12;C07D405/12;C07D407/12;C07D409/12;C07D413/12;C07D417/12;C07D471/04;C07D487/04 |
主分类号 |
A61K31/536 |
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