发明名称 HETEROMONOCYCLIC COMPOUND AND USE THEREOF
摘要 A compound represented by the formula (I): wherein R1 is an oxo group, -N-R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, -CO-R8 or -O-R8', or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.
申请公布号 US2009176812(A1) 申请公布日期 2009.07.09
申请号 US20080114048 申请日期 2008.05.02
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 KUROITA TAKANOBU;SAKAMOTO HIROKI;IGAWA HIDEYUKI;SASAKI MINORU;ASANO KOUHEI;MAEKAWA TSUYOSHI;FUJI KOJI
分类号 A61K31/505;A61P9/10;C07D239/54;C07D413/08 主分类号 A61K31/505
代理机构 代理人
主权项
地址