NOVEL PROCESS FOR PREPARATION OF O-DESMETHYLVENLAFAXINE

摘要

The present invention relates to the novel processes for the preparation of 4-(2- (dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol, commonly known as O- desmethylvenlafaxine of formula (I) and its pharmaceutically acceptable salts thereof The present invention also relates to the novel process for the preparation of O- desmethylvenlafaxine of formula (I) and its pharmaceutically acceptable salts thereof formula (V) or formula (VI) formula (I) or formula (VII) wherein, R is hydrogen, methoxyethoxymethyl (MEM), methoxymethyl (MOM), aryloyl, arylsulfonyl, tetrahydropyranyl or substituted silyl.