发明名称 Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
摘要 The present invention provides liquid formulations of antibodies or fragments thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of the antibodies or antibody fragments, even during long periods of storage. In particular, the present invention provides liquid formulations of antibodies or fragments thereof that immunospecifically bind to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides methods of preventing, treating or ameliorating one or more symptoms associated with RSV infection utilizing the liquid formulations of the present invention.
申请公布号 US2009175883(A1) 申请公布日期 2009.07.09
申请号 US20080075197 申请日期 2008.03.10
申请人 MEDIMMUNE, INC. 发明人 OLIVER CYNTHIA N.;ALLAN CHRISTIAN B.;CHANG STEPHEN T.
分类号 A61K39/395;A61K9/00;A61K39/42;A61K47/18;A61P31/12;C07K16/10 主分类号 A61K39/395
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