CRYSTAL STRUCTURE OF PROPROTEIN CONVERTASE 9 (PCSK9) AND USES THEREOF

摘要

The invention provides a crystallized PCSK9 molecule. The three-dimensional coordinates of the crystal structure of PCSK9 are obtained by X-ray diffraction. The coordinates can be used for studying the PCSK9 structure and designing, screening and developing compounds that modulate PCSK9 activity.