发明名称 |
IMPROVED THERAPEUTIC METHODS AND COMPOSITIONS COMPRISING CHROMAN RING COMPOUNDS |
摘要 |
The instant invention concerns chroman ring derivative compounds such as vitamin E derivatives and methods for their use. In certain aspects, methods for treating subjects comprising Arg, JNK, p73, NOXA or FOXO1 positive cancers are provided. In still further aspects, methods for treating cell proliferative disease such as cancer by administration of a chroman ring compound in conjunction with a P13 or Akt kinase inhibitor are described. |
申请公布号 |
WO2009012096(A3) |
申请公布日期 |
2009.07.09 |
申请号 |
WO2008US69512 |
申请日期 |
2008.07.09 |
申请人 |
RESEARCH DEVELOPMENT FOUNDATION;SANDERS, BOB, G.;KLINE, KIMBERLY |
发明人 |
SANDERS, BOB, G.;KLINE, KIMBERLY |
分类号 |
A61K31/355;A61K31/353;A61P35/00 |
主分类号 |
A61K31/355 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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