发明名称 |
DDR1-MEDIATED CELL PURIFICATION OF PANCREATIC ENDOCRINE CELLS THROUGH THEIR PROGENITORS |
摘要 |
<p>The invention relates to a method of identifying, obtaining and/or quantifying a culture of pancreatic cells selected from the group consisting of ductal/endocrine progenitor cells, endocrine progenitor cells, early endocrine cells, and fully differentiated endocrine cells. Also contemplated is a method of expanding the numbers of such cells as well as sorting such cells. The invention further relates to a selective cell surface marker, DDR1, that permits the selection of a unique subset of cells with pancreatic endocrine progenitor phenotype. Furthermore, the invention relates to isolated cells selected from such cells and compositions thereof.</p> |
申请公布号 |
WO2009083502(A1) |
申请公布日期 |
2009.07.09 |
申请号 |
WO2008EP68061 |
申请日期 |
2008.12.19 |
申请人 |
NOVO NORDISK A/S;HALD, JACOB;MADSEN, OLE DRAGSBAEK;SERUP, PALLE |
发明人 |
HALD, JACOB;MADSEN, OLE DRAGSBAEK;SERUP, PALLE |
分类号 |
C07K14/705;C12N5/071;C12N5/074;G01N33/566 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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