TUMOR IMAGING COMPOUND

摘要

PROBLEM TO BE SOLVED: To provide novel amino acid compounds for use in detecting and evaluating brain and body tumors. SOLUTION: The amino acid compounds have a high specificity on the target site, when being in vivo administered, and for example, 2-amino-3-fluoro-2-methyl propane derivatives can be cited as preferable amino acid compounds, and the derivatives include a compound in which F of the derivatives is18F. The invention further includes pharmaceutical compositions of anα-amino acid moiety attached to any one of 4-, 5-, or 6-membered carbon rings. The labeled amino acid compounds are useful as an imaging agent in detecting and/or monitoring tumors in a subject by Positron Emission Tomography (PET) and Single Photon Emission Computer Tomography (SPECT). COPYRIGHT: (C)2009,JPO&INPIT