TOPICAL COMPOSITIONS CONTAINING DESTHIOBIOTIN AND ITS DERIVATIVES AND A METHOD OF TREATING SKIN

摘要

Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising desthiobiotin and certain desthiobiotin analogues. These compounds are effective in stimulating LOXL-1 activity and can thus increase elastin remodeling and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of reduced elastin function.