发明名称 ZINC FINGER BINDING DOMAIN FOR NUCLEOTIDE SEQUENCE ANN
摘要 <P>PROBLEM TO BE SOLVED: To provide polypeptides that contain from 2 to 12 zinc finger-nucleotide binding regions that bind to nucleotide sequences of the formula (ANN) 2-12. <P>SOLUTION: The polypeptide that contains from 2 to 12 zinc finger-nucleotide binding regions contains a nucleotide binding region wherein at least one of the peptides has a specific sequence. The polynucleotide encodes such the polypeptide. The method of regulating gene expression with such the polypeptide and the polynucleotide is also provided. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009148272(A) 申请公布日期 2009.07.09
申请号 JP20090004822 申请日期 2009.01.13
申请人 NOVARTIS AG;SCRIPPS RES INST:THE 发明人 BARBAS CARLOS F;DREIER BIRGIT
分类号 C12N15/09;A61K31/7088;A61K38/00;A61P31/12;A61P43/00;C07K7/06;C07K14/46;C07K14/47;C07K19/00;C12N15/12;C12N15/85 主分类号 C12N15/09
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