发明名称 |
PROCESS FOR OBTAINING A CONCENTRATE OF VON WILLEBRAND FACTOROR A COMPLEX OF FACTOR VIII/VON WILLEBRAND FACTOR AND USE OF THE SAME |
摘要 |
Process for the preparation of a concentrate of Von Willebrand Factor or a complex of Factor VIII/Von Willebrand Factor and use of the same. The process is characterised by the preparation of a solution of Von Willebrand Factor or a complex of Factor VIII/Von Willebrand Factor which contains VWF and a concentration of up to 12 IU VWF:RCo/ml and a Von Willebrand Factor/Factor VIII ratio of 0.4 or more; and then proceeding with nanofiltration of the solution prepared in a) through a filter having a pore size of less than 35 nanometres.
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申请公布号 |
CA2645701(A1) |
申请公布日期 |
2009.07.08 |
申请号 |
CA20082645701 |
申请日期 |
2008.12.03 |
申请人 |
GRIFOLS, S.A. |
发明人 |
FARO TOMAS, MARIA MERCEDES;JORQUERA NIETO, JUAN IGNACIO;RISTOL DEBART, PERE |
分类号 |
C07K14/745;A61K38/36;A61K38/37;A61P7/04;C07K1/34;C07K14/755 |
主分类号 |
C07K14/745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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