发明名称 |
Implantable active ingredient depot |
摘要 |
The invention relates to an implantable active ingredient depot for therapeutically active substances. The fields of application are in medicine and the pharmaceutical industry. The implantable active ingredient depot is constituted of a lipid matrix capable of forming cubic phases into which modifier molecules have been integrated and contains pharmaceutically active substances. A preferred lipid matrix is monooleine. The implantable depot of the invention is useful for the treatment of tumors in oncological therapy and in gene therapy. A rational membrane design allows control of the release of the active ingredients over time and also control of the amount released.
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申请公布号 |
US7556827(B1) |
申请公布日期 |
2009.07.07 |
申请号 |
US20000048840 |
申请日期 |
2000.08.04 |
申请人 |
MAX-DELBRUECK-CENTRUM-FUER MOLEKULARE MEDIZIN |
发明人 |
RESZKA REGINA;SCHLUTER ROLAND |
分类号 |
A61K9/14;A61K9/00;A61K9/127;A61K9/22;A61K31/132;A61K31/337;A61K31/437;A61K31/485;A61K31/704;A61K31/7072;A61K31/7105;A61K31/711;A61K33/24;A61K38/00;A61K45/00;A61K47/24;A61K47/34;A61K48/00;A61P9/10;A61P25/04;A61P25/16;A61P25/28;A61P29/00;A61P35/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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