| 发明名称 |
Stoichiometric conjugates of biocompatible polymers at the unpaired cysteine residue of the wild-type G-CSF |
| 摘要 |
The present invention relates to a conjugate of a biocompatible polymer and a G-CSF bonded through a thiol group of a dysteine residue in G-CSF at a 1:1 molar ratio, and methods of preparation thereof.
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| 申请公布号 |
US7557195(B2) |
申请公布日期 |
2009.07.07 |
| 申请号 |
US20040508721 |
申请日期 |
2004.09.20 |
| 申请人 |
BIOPOLYMED, INC. |
发明人 |
PARK MYUNG-OK |
| 分类号 |
A61K38/19;A61K39/00;A61K45/00;C07K14/535;C08H1/00 |
主分类号 |
A61K38/19 |
| 代理机构 |
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