发明名称 Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
摘要 Compounds and a method of synthesis of compounds of formula (Ia) or (Ib): and salts, solvates, and chemically protected forms thereof, wherein the dotted lines indicate the optional presence of a double bond between C1 and C2 or C2 and C3; R2 and R3 are independently selected from -H, -O, -CH2, -CN, -R, OR, halo, -CH-R, O-SO2-R, CO2R and COR; R10 is a carbamate-based nitrogen protecting group; and R11 is an oxygen protecting group.
申请公布号 US7557099(B2) 申请公布日期 2009.07.07
申请号 US20050598482 申请日期 2005.03.01
申请人 SPIROGEN LIMITED 发明人 HOWARD PHILIP WILSON;KANG GYOUNG-DONG
分类号 C07D519/00;A61K31/55;C07D487/04 主分类号 C07D519/00
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