Crystallization of the catalytic domain of human phosphodiesterase 4-D3 (PDE4-D3)
摘要
Provided are crystals relating to human phosphodiesterase 4-D3 (PDE4-D3), methods for forming crystals comprising PDE4-D3 and crystals comprising PDE4-D3 co-crystallized with a ligand molecule, and methods of using crystals comprising PDE4-D3.
申请公布号
US7556950(B1)
申请公布日期
2009.07.07
申请号
US20040836040
申请日期
2004.04.29
申请人
TAKEDA SAN DIEGO, INC.
发明人
BROOUN ALEXEI;CHIEN ELLEN;DOUGAN DOUGLAS R.;KRAUS MICHELLE L.;MOL CLIFFORD D.;SNELL GYORGY