发明名称 Compounds Comprising Short Aminoalcohol Chains and Metal Complexes for Medical Imgaing
摘要 The present invention relates to a compound of formula (II) chosen from (IIa) and (IIb) or of formula (VI) chosen from (VIa) and (VIb) of following general formulae: in which: X1, X2, X3, X4 and X5 represent, independently of one another, L-Y in which L represents a C1-C3 alkyl group, preferably (CH2), with n=1 to 3, Y represents -CONH2, -CO-NR7R8 or -NR7-CO-R8, or an isomer, an enantiomer or a diastereoisomer of these or their mixtures or a pharmaceutically acceptable salt of the compounds of formulae (VIa) and (VIb). It also relates to a complex of these compounds with a paramagnetic metal or a radionuclide and their use in diagnostic methods.
申请公布号 US2009169479(A1) 申请公布日期 2009.07.02
申请号 US20060083092 申请日期 2006.10.09
申请人 GUERBET 发明人 PORT MARC
分类号 A61K31/395;A61K31/439;A61K31/555;A61K49/12;C07D257/02;C07D471/08;C07F15/00;C12N15/63 主分类号 A61K31/395
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