发明名称 |
SUBSTITUTED 2,5-DIHYDRO-3H-PYRAZOLO[4,3-C]PYRIDAZIN-3-ONE DERIVATIVES, PREPARATION THEREOF AND USE OF SAME AS CANNABINOID CB1 RECEPTOR LIGANDS |
摘要 |
The invention relates to compounds having the formula (I), wherein R1 represents: a substituted or non-substituted (C1-C12)alkyl; a non aromatic (C3-C12) carbocylic substituted or non substituted radical; a substituted or non substituted phenyl; a substituted or non substituted benzyl; a substituted or non substituted phenethyl; a benzhydryl; a benzhydrylmethyl; a heterocyclic aromatic radical; R2 represents a non substituted or substituted phenyl; R3 represents a substituted or non substituted phenly; R4 represents a hydrogen atom, a (C1-C-4)alkyl, a (C1-C4)alcoxy, a hydroxy; AIk represents a substituted or non substituted (C1-C4)alkyl. The invention also relates to the method for preparing same and to the use thereof in therapeutics as central and/or peripheral cannabinoid CB1 receptor ligands.
|
申请公布号 |
WO2008068424(A8) |
申请公布日期 |
2009.07.02 |
申请号 |
WO2007FR01889 |
申请日期 |
2007.11.19 |
申请人 |
SANOFI-AVENTIS;CONGY, CHRISTIAN;DOS SANTOS, VICTOR;RINALDI-CARMONA, MURIELLE;ROUQUETTE, ARNAUD;VAN BROECK, DIDIER |
发明人 |
CONGY, CHRISTIAN;DOS SANTOS, VICTOR;RINALDI-CARMONA, MURIELLE;ROUQUETTE, ARNAUD;VAN BROECK, DIDIER |
分类号 |
C07D487/04;A61K31/5025;A61P3/00;A61P25/00;C07D495/04 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|