发明名称 |
PEPTIDE SUBSTANCE REVEALING AN IMMUNOGEROPROTECTIVE EFFECT, PHARMACEUTICAL COMPOSITION ON ITS BASE AND THE METHOD OF ITS APPLICATION |
摘要 |
The invention is related to the medicinal means of prevention and correction of age-related disorders of cellular and humoral immunity and may be used as a medication revealing an immunogeroprotective effect. There is proposed a peptide glutamyl-aspartyl-proline with general formula H-Glu-Asp-Pro-OH sequence 1 [SEQ ID NO:1], revealing an immunogeroprotective effect. There is proposed a pharmaceutical composition revealing an immunogeroprotective effect containing an effective amount of peptide glutamyl-aspartyl-proline with general formula H-Glu-Asp-Pro-QH sequence 1 [SEQ ID NO:1] as its active base. In this case such pharmaceutical composition exists in the form suitable for parenteral administration. There is proposed a method of prevention and/or correction of age-related disorders of cellular and humoral immunity by stimulating the processes of lymphocytes proliferation and differentiation, such method consisting in the administration to a patient of a pharmaceutical composition containing an effective amount of peptide glutamyl-aspartyl-proline with general formula: H-Glu-Asp-Pro-OH sequence 1 [SEQ ID NO:1] in the dose of 0.01-100 mug/kg of body weight as an active base at least once a day during a period necessary for attaining a therapeutic effect. In this case the pharmaceutical composition is administered parenterally.
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申请公布号 |
US2009170785(A1) |
申请公布日期 |
2009.07.02 |
申请号 |
US20070298423 |
申请日期 |
2007.03.02 |
申请人 |
OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU 'SIA PEPTIDES' |
发明人 |
KHAVINSON VLADIMIR KHATSKELEVICH;GRIGORIEV EVGENY IOSIFOVICH;MALININ VLADIMIR VICTOROVICH;RYZHAK GALINA ANATOLIEVNA |
分类号 |
A61K38/06;C07K5/08 |
主分类号 |
A61K38/06 |
代理机构 |
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代理人 |
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地址 |
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