发明名称 |
OPTOELECTRONIC TWEEZERS FOR MICROPARTICLE AND CELL MANIPULATION |
摘要 |
An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 mum or less. The apparatus is referred to as optoelectric tweezers (OET) and provides a number of advantages over conventional optical tweezers, in particular the ability to perform operations in parallel and over a large area without damage to living cells. The OET device generally comprises a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a change in the electric field pattern. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells. The OET preferably includes a microscopic imaging means to provide feedback for the optical manipulation, such as detecting position and characteristics wherein the light patterns are modulated accordingly.
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申请公布号 |
US2009170186(A1) |
申请公布日期 |
2009.07.02 |
申请号 |
US20050105304 |
申请日期 |
2005.04.12 |
申请人 |
WU MING CHIANG;CHIOU PEI YU;OHTA AARON T |
发明人 |
WU MING CHIANG;CHIOU PEI YU;OHTA AARON T. |
分类号 |
C12M1/36;B01J19/08;C12M3/04 |
主分类号 |
C12M1/36 |
代理机构 |
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主权项 |
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地址 |
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