摘要 |
Method for the analysis of breast cancer disorders, comprising determining the genomic methylation status of one or more CpG dinucleotides in a sequence selected from the group of sequences according to SEQ ID NO. 1 to 10 and/or SEQ ID NO. 50 to SEQ ID NO. 60. Optionally, additionally following steps are performed, the one or more results from the methylation status test is input into a classifier that is obtained from a Diagnostic Multi Variate Model, calculating a likelihood as to whether the sample is from a normal tissue or an breast cancer tissue and/or, calculating an associated p-value for the confidence in the prediction. |
申请人 |
KONINKLIJKE PHILIPS ELECTRONICS N. V.;COLD SPRING HARBOR LABORATORY;KAMALAKARAN, SITHARTHAN;LUCITO, ROBERT;HICKS, JAMES BRUCE;ZHAO, XIAOYUE;KENDALL, JUDE |
发明人 |
KAMALAKARAN, SITHARTHAN;LUCITO, ROBERT;HICKS, JAMES BRUCE;ZHAO, XIAOYUE;KENDALL, JUDE |