METHODS AND COMPOSITIONS FOR MODULATING BMP-10 ACTIVITY

摘要

Methods and compositions for modulating cardiac, renal and vascular cell function and homeostasis using agonists and antagonists of BMP-IO are disclosed. In particular, methods for treating, preventing and/or diagnosing BMP-10-associated vascular, renal, fibrotic and cardiac conditions and/or disorders are disclosed. Screening methods for evaluating BMP-IO modulators, e.g., agonists and antagonists, are also disclosed.