QUINOLINE DERIVATIVES WITH AFFINITY FOR THE 5-HT2B RECEPTOR

摘要

The present invention relates to 8-[4-(1,1 -dioxidotetrahydro-2H-thiopyran-4-yl)-1- piperazinyl]-2-methylquinoline or a pharmaceutically acceptable salt thereof (compounds of formula (I)) which bind to the 5-HT2B receptor and are capable of interfering with the effects of 5-hydroxytryptamine (5-HT) at the 5-HT2B receptor; to pharmaceutical compositions containing them; and to the use of such compounds in therapy.