发明名称 |
METHODS OF INHIBITING TUMOR GROWTH USING TTK ANTAGONISTS |
摘要 |
The present invention relates to methods for treating TTK positive breast cancers or soft-tissue sarcomas in a mammalian subject by administering a therapeutically effective amount of a TTK antagonist. The invention also provides compositions comprising a TTK antagonist and a HER-2 antagonist, as well as methods of diagnosing a basal-like breast cancer and methods of determining the prognosis of a subject having a cancer by assessing expression of TTK in a tumor sample from a subject. |
申请公布号 |
WO2009079768(A1) |
申请公布日期 |
2009.07.02 |
申请号 |
WO2008CA02228 |
申请日期 |
2008.12.19 |
申请人 |
UNIVERSITY HEALTH NETWORK;PAN, GUOHUA |
发明人 |
PAN, GUOHUA |
分类号 |
A61K39/395;A61K31/7105;A61K45/00;A61K48/00;A61P35/00;A61P35/04;C12Q1/48;C12Q1/68;G01N33/574;G01N33/68 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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