发明名称 |
Triptolide Derivatives for Modulation of Apoptosis and Immunosuppression |
摘要 |
Variously substituted carbonate and carbamate derivatives of triptolide compounds have good aqueous solubility and convert to biologically active compounds in vivo, at a rate which can be modulated by varying the substitution on the prodrug. The prodrugs are useful as immunosuppressive, anti-inflammatory and anticancer agents.
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申请公布号 |
US2009171103(A1) |
申请公布日期 |
2009.07.02 |
申请号 |
US20090366528 |
申请日期 |
2009.02.05 |
申请人 |
DAI DONGCHENG;MUSSER JOHN H;LENNOX EDWIN S |
发明人 |
DAI DONGCHENG;MUSSER JOHN H.;LENNOX EDWIN S. |
分类号 |
C07D493/22;A61K31/365;A61P35/00;A61P37/06 |
主分类号 |
C07D493/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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