| 发明名称 |
PROCESS FOR PREPARATION OF OLOPAT ADINE HYDROCHLORIDE |
| 摘要 |
Disclosed herein is a process for preparation of compound 11 - (Z) - [3 - (Dimethylamino) propylidene] - 6, 11 - dihydrodibenz [b, e] oxepin -2 - yl - acetic acid (Olopatadine) and its pharmaceutically acceptable salt; comprising reacting carboxylic acid protected 11 - oxo - 6, 11 - Dihydrodibenz [b, e] oxepin - 2 - acetic acid with 3 - dimethylaminopropyl triphenyl phosphonium halide in presence of a suitable base and an organic solvent. |
| 申请公布号 |
WO2009081417(A2) |
申请公布日期 |
2009.07.02 |
| 申请号 |
WO2008IN00780 |
申请日期 |
2008.11.20 |
| 申请人 |
INDOCO REMEDIES LIMITED;VYAS KETAN DHANSUKHLAL;NAIR RANJEET;CHAVAN RAJENDRA VASANTRAO;SHELKE YOGESH VISHWAS;PANANDIKAR, ADITI MILIND |
发明人 |
VYAS KETAN DHANSUKHLAL;NAIR RANJEET;CHAVAN RAJENDRA VASANTRAO;SHELKE YOGESH VISHWAS;PANANDIKAR, ADITI MILIND |
| 分类号 |
C07D313/12 |
主分类号 |
C07D313/12 |
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