The present invention relates to a new process for the preparation of macrocyclic HCV protease inhibitor compounds of the formula (VII) wherein R1 is an amino protecting group and X is halogen by way of a ring closing metathesis approach.
申请公布号
WO2009080542(A1)
申请公布日期
2009.07.02
申请号
WO2008EP67309
申请日期
2008.12.11
申请人
F. HOFFMANN-LA ROCHE AG;HILDBRAND, STEFAN;PUENTENER, KURT;SCALONE, MICHELANGELO