发明名称 |
ENHANCING DISEASE RESISTANCE AGAINST RNA VIRAL INFECTIONS WITH INTRACYTOPLASMIC PATHOGEN SENSORS |
摘要 |
<p>The present disclosure provides compositions and methods for enhancing resistance to viral infections. The compositions include adenovirus vectors containing nucleic acid molecules encoding CARD domains from RIG-I and MDA5, recombinant adenoviruses and immunogenic compositions comprising such recombinant adenovirus vectors and adenoviruses. Methods for enhancing resistance to viral infections involving administering such adenovirus vectors or recombinant adenovirus are also provided.</p> |
申请公布号 |
EP2073818(A2) |
申请公布日期 |
2009.07.01 |
申请号 |
EP20070844327 |
申请日期 |
2007.10.16 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES |
发明人 |
SAMBHARA, SURYAPRAKASH;GUO, ZHU |
分类号 |
A61K31/711;C12N7/01;C12N15/861 |
主分类号 |
A61K31/711 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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