发明名称 |
PHARMACEUTICAL FORMULATION COMPRISING METFORMIN AND REPAGLINIDE |
摘要 |
The invention is related to a pharmaceutical composition comprising repaglinide in combination with metformin or a salt thereof in unit dosage form wherein a pre-formulation of the repaglinide has a pH independent dissolution profile and a relative humidity of less than about 25% prior to mixing with the metformin or a salt thereof; and optionally one or more pharmaceutically acceptable excipients and to a method for its preparation. |
申请公布号 |
EP2073796(A1) |
申请公布日期 |
2009.07.01 |
申请号 |
EP20070820729 |
申请日期 |
2007.09.28 |
申请人 |
NOVO NORDISK A/S |
发明人 |
HOEJGAARD, BENT;KNUDSEN, BREIAN;RASMUSSEN, STELLA RUDKJAER;JACOBSEN, LENE ORUP |
分类号 |
A61K9/16;A61K9/20;A61K31/155;A61K31/451 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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