发明名称 |
ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES |
摘要 |
The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds. |
申请公布号 |
KR20090069281(A) |
申请公布日期 |
2009.06.30 |
申请号 |
KR20097006628 |
申请日期 |
2007.09.07 |
申请人 |
INDUSTRIAL RESEARCH LIMITED;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
CLINCH KEITH;EVANS GARY BRIAN;FURNEAUX RICHARD HUBERT;KELLY PETER MICHAEL;SCHRAMM VERN L.;TYLER PETER CHARLES;WOOLHOUSE ANTHONY DAVID;GULAB SHIVALI ASHWIN |
分类号 |
C07D487/04;A61K31/519;A61P17/06;A61P31/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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