发明名称 |
Use of des-Aspartate-angiotensin I as an agent for the treatment and prevention of glomerulosclerosis and renal failure |
摘要 |
The present invention relates generally to a method for the treatment and/or prophylaxis of renal-related disorders. More particularly, the present invention contemplates a method for the treatment and/or prophylaxis of glomerulosclerosis and/or end stage renal failure and/or related conditions. The method of the present invention is preferably practised by the administration of a derivative of angiotensin I. Generally, but not exclusively, the angiotensin I derivative exhibits anti-angiotensin II properties. In a preferred embodiment, the angiotensin I is des-Aspartate-angiotensin I or a derivative, homologue or analogue thereof. The present invention further contemplates compositions for use in the treatment and/or prophylaxis of renal-related disorders such as but not limited to glomerulosclerosis and/or end stage renal failure.
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申请公布号 |
US7553928(B2) |
申请公布日期 |
2009.06.30 |
申请号 |
US20020269458 |
申请日期 |
2002.10.11 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE |
发明人 |
SIM MENG KWOON;TAN CHORH CHUAN |
分类号 |
A61K38/00;A61K38/22;A61K38/08;A61P13/12;A61P43/00 |
主分类号 |
A61K38/00 |
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