发明名称 |
AGGLOMERATION OF THE CALCIUM-CONTAINING COMPOUND BY MEANS OF ROLLER COMPACTION |
摘要 |
The present invention relates to a particulate material and a solid dosage form notably tablets comprising a regularly shaped calcium-containing compound such as a calcium salt as a therapeutically and/or prophylactically active substance and a pharmaceutically acceptable sugar alcohol such as, e.g., sorbitol and/or isomalt that has a micro structure as evidenced by SEM. The invention also relates to a process for the preparation of the particulate material and solid dosage form. The process involves agglomeration of the calcium-containing compound and the pharmaceutically acceptable sugar alcohol by means of roller compaction. The particulate material obtained by roller compaction is suitable for use in the further processing of the particulate material into e.g. tablets such as chewing tablets. |
申请公布号 |
EA011746(B1) |
申请公布日期 |
2009.06.30 |
申请号 |
EA20060002175 |
申请日期 |
2005.05.24 |
申请人 |
NYCOMED PHARMA AS |
发明人 |
MATHIESEN JACOB;NIELSEN CARSTEN, MARTINI;OLSEN PEDER, MOHR;BERTELSEN PAUL, EGON |
分类号 |
A61K9/16;A61K9/00;A61K9/20;A61K33/06 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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