| 发明名称 |
SUBSTITUTED BENZAZOLES AND USE THEREOF AS INHIBITORS OF RAF KINASE |
| 摘要 |
New substituted benzazole compounds of formula (I), compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer. |
| 申请公布号 |
EA011890(B1) |
申请公布日期 |
2009.06.30 |
| 申请号 |
EA20060000689 |
申请日期 |
2004.09.29 |
| 申请人 |
NOBARTIS VACCINES AND DIAGNOSTICS, INC. |
发明人 |
AMIRI PAYMAN;FANTLE WENDY;LEVINE BARRY, HASKELL;POON DANIEL, J.;RAMURTHY SAVINTHRI;RENHOWE PAUL, A.;SUBRAMANIAN SHARADHA;SUNG LEONARD |
| 分类号 |
A61K31/41;A61P35/00;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D407/14;C07D409/14;C07D413/04;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D453/02;C07D471/08 |
主分类号 |
A61K31/41 |
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