PHOSPHONATE-SUBSTITUTED PYRIMIDINE COMPOUNDS (VARIANTS), METHOD FOR PREPARATION THEREOF (VARIANTS), PHARMACEUTICAL COMPOSITION BASED THEREON AND METHOD FOR THE TREATMENT OF VIRAL INFECTION

摘要

Novel compounds are provided having formula (I)where R, R, R, R, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).