发明名称 DRUG DELIVERY SYSTEM FOR ADMINISTRATION OF A WATER SOLUBLE, CATIONIC AND AMPHIPHILIC PHARMACEUTICALLY ACTIVE SUBSTANCE
摘要 A drug delivery system (DDS) for administration of a water soluble, cationic, and amphiphilic pharmaceutically active substance (API) which DDS comprises poorly water soluble nanoparticles formed by the API together with a Na-salt of N-all- trans-retinoyl cysteic acid methyl ester and/or a Na-salt of N-13-cis-retinoyl cysteic acid methyl ester. A pharmaceutical composition comprising such a DDS. Methods for preparation of such a DDS and such a pharmaceutical composition. Use of such a DDS and pharmaceutical composition for treatment of cancer.
申请公布号 WO2009078756(A1) 申请公布日期 2009.06.25
申请号 WO2007SE01129 申请日期 2007.12.19
申请人 ARDENIA INVESTMENTS, LTD.;ALEKSOV, JULIAN;LOKOT, IGOR 发明人 ALEKSOV, JULIAN;LOKOT, IGOR
分类号 A61K47/48;A61K9/14;A61P35/00 主分类号 A61K47/48
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