发明名称 Novel Protein Kinase B Inhibitors - 060
摘要 The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).
申请公布号 US2009163524(A1) 申请公布日期 2009.06.25
申请号 US20080249477 申请日期 2008.10.10
申请人 ASTRAZENECA AB 发明人 JOHNSON PAUL DAVID;LEACH ANDREW;LUKE RICHARD WILLIAM ARTHUR;MATUSIAK ZBIGNIEW STANLEY;MORRIS JEFFREY JAMES
分类号 A61K31/519;A61P35/00;C07D487/04 主分类号 A61K31/519
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