发明名称 Process for Preparing Creatine, Creatine Monohydrate or Guanidinoacetic Acid
摘要 A process for producing creatine, creatine monohydrate or guanidinoacetic acid is proposed, wherein firstly N-methylethanolamine or ethanolamine is catalytically dehydrogenated in each case in alkaline solution and the sarcosinate or glycinate solutions that are obtained in this manner are finally reacted under acidic conditions with a guanylating agent such as for example O-alkylisourea or cyanamide. In this manner products are obtained in high yields and very good purity where in contrast to the prior art no traces whatsoever of hydrocyanic acid, formaldehyde, chloroacetic acid or ammonia are present. The formation of the toxicologically critical dihydrotriazine is also avoided.
申请公布号 US2009163739(A1) 申请公布日期 2009.06.25
申请号 US20070226040 申请日期 2007.04.05
申请人 THALHAMMER FRANZ;GASTNER THOMAS 发明人 THALHAMMER FRANZ;GASTNER THOMAS
分类号 C07C277/08 主分类号 C07C277/08
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