<p>An improved method for preparing protein conjugates comprising reacting primary amino groups of a first protein with a first bifunctional linker to form a first protein-linker moiety; reacting a second protein with a second bifunctional linker to form a second protein-linker moiety and then reacting the first and second protein-linker moieties to form a protein conjugate.</p>
申请公布号
WO2009077438(A1)
申请公布日期
2009.06.25
申请号
WO2008EP67378
申请日期
2008.12.12
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A.;BIEMANS, RALPH, LEON;DUVIVIER, PIERRE