发明名称 |
Anchor-Assisted Fragment Selection and Directed Assembly |
摘要 |
The invention provides methods for compound and lead generation and discovery. In particular, the present invention provides a method for generating compounds and for selecting compounds that bind to a target. The present invention provides a way by which anchors (e.g., weak binders) and anchor-scaffold conjugates can be evolved into new generations of compounds having improved target binding and other desired pharmaceutical properties through control of both synthetic input and selection criteria.
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申请公布号 |
US2009163371(A1) |
申请公布日期 |
2009.06.25 |
申请号 |
US20060915533 |
申请日期 |
2006.05.31 |
申请人 |
STERN ANDREW M;HARBESON SCOTT L;DRIGGERS EDWARD M;SPEAR KERRY L |
发明人 |
STERN ANDREW M.;HARBESON SCOTT L.;DRIGGERS EDWARD M.;SPEAR KERRY L. |
分类号 |
C40B30/04;C12Q1/68 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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