发明名称 SUBSTITUTED AMINOALKANEPHOSPHONIC ACID FOR TREATING NEUROPATHIC PAIN, AFFECTIVE AND ATTENTION DISORDER, SCHIZOPHRENIA, TINNITUS, MYOPIA AND OTHER OCULAR DISORDER
摘要 PROBLEM TO BE SOLVED: To provide a compound for treating neuropathic pain, affective and attention disorders, schizophrenia, tinnitus, myopia and other ocular disorders. SOLUTION: The invention relates to a free form or a pharmaceutically permitted salt form of substituted aminoalkanephosphonic acid, ä[(7-nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amino]-methyl}-phosphonic acid, (R)-N-(2,3-dioxo-7-nitro-1,2,3,4-tetrahydroquinoxalin-5-ylmethyl)-α-(ethylamino)-ethylphosphonic acid, or (S)-N-(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-ylmethyl)-α-aminoethylphosphonic acid, in treating neuropathic pain, affective and attention disorders, schizophrenia, tinnitus, myopia and other ocular disorders. COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009137995(A) 申请公布日期 2009.06.25
申请号 JP20090012152 申请日期 2009.01.22
申请人 NOVARTIS AG 发明人 LINGENHOEHL KURT;AUBERSON YVES;FOX ALYSON;NEIJT HANS CH;KALKMAN HANS O
分类号 A61K31/662;A61K31/675;A61P25/00;A61P25/02;A61P25/04;A61P25/14;A61P25/18;A61P27/02;A61P27/10;A61P27/16 主分类号 A61K31/662
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