发明名称 PREVENTIVE OR THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE
摘要 The invention relates to a pharmaceutical composition for preventing or treating an inflammatory bowel disease comprising 7,8-dimethoxy-4(5H),10-dioxo-1H-1,2,3-triazolo[4,5-c][1]benzoazepine, a prodrug thereof, preferably 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzoazepine as the prodrug, or a pharmacologically acceptable salt thereof. The pharmaceutical composition according to the invention is effective in the prevention and treatment of an inflammatory bowel disease and has few side effects. In particular, the pharmaceutical composition according to the invention can exhibit a potent preventive effect and therapeutic effect also on a severe case showing resistance to existing therapeutic agents.
申请公布号 CA2709119(A1) 申请公布日期 2009.06.25
申请号 CA20082709119 申请日期 2008.12.17
申请人 MEIJI SEIKA KAISHA, LTD. 发明人 NINOMIYA, TOMOHISA;SHISHIKURA, TAKASHI;UCHIDA, MITSUHIRO;TAKAHATA, SHO;HOSHINA, YUKARI;KAWANO, KEN-ICHI
分类号 A61K31/55;A61P1/04;C07D487/04 主分类号 A61K31/55
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