发明名称 |
Processes for Highly Enantio- and Diastereoselective Synthesis of Acyclic Epoxy Alcohols and Allylic Epoxy Alcohols |
摘要 |
The inventive subject matter relates to novel processes for making an epoxy alcohol from an aldehyde, comprising the steps of: (a) adding (i) an organozinc compound or (ii) divinylzinc compound and an diorganozinc compound to said aldehyde in the presence of a first catalyst to form an allylic alkoxide compound; and (b) epoxidizing said allylic alkoxide compound in the presence of an oxidant and a second catalyst.
|
申请公布号 |
US2009163728(A1) |
申请公布日期 |
2009.06.25 |
申请号 |
US20050592075 |
申请日期 |
2005.03.09 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
WALSH PATRICK;LURAIN ALICE E.;KELLY ANN R.;MAESTRI AARON G. |
分类号 |
C07D301/03;C07D301/14;C07D303/14 |
主分类号 |
C07D301/03 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|