| 发明名称 |
O-ALKYLATED RAPAMYCIN DERIVATIVE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a medical appliance using an O-alkylrapamycin derivative and its compound. <P>SOLUTION: A stent includes O-alkylrapamycin derivative formed by reaction between rapamycin and alkyl triflate in an organic solvent or, in concrete terms, a coating of 40-O-[(2'-ethoxy)ethyl] rapamycin, and is configured to be indwelled in a lesioned part of the blood vessel and to prevent the restenosis in the lesioned part. <P>COPYRIGHT: (C)2009,JPO&INPIT |
| 申请公布号 |
JP2009136686(A) |
申请公布日期 |
2009.06.25 |
| 申请号 |
JP20080329108 |
申请日期 |
2008.12.25 |
| 申请人 |
TERUMO CORP;BIOSENSORS INTERNATL GROUP LTD |
发明人 |
KAWANISHI TETSUAKI;ISOZAKI MASASHI |
| 分类号 |
A61L31/00;A61F2/82;A61K31/436;A61M29/02;A61P31/10;A61P35/00;A61P37/06;C07D498/18 |
主分类号 |
A61L31/00 |
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