An improved method for preparing protein conjugates comprises reacting primary amino groups of a first protein with a one group of a bifunctional linker and reacting a second protein with a second group on te same bifuntional linker to form a protein conjugate.
申请公布号
WO2009077436(A2)
申请公布日期
2009.06.25
申请号
WO2008EP67376
申请日期
2008.12.12
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A.;BIEMANS, RALPH, LEON;DUVIVIER, PIERRE