发明名称 |
STRAIN FOR BUTANOL PRODUCTION |
摘要 |
Using screening of transposon random insertion mutants, genes involved in a complex that is a three-component proton motive force-dependent multidrug efflux system were found to be involved in E. coli cell response to butanol. Reduced production of the AcrA and/or AcrB proteins of the complex confers increased butanol tolerance. E. coli strains with reduced AcrA or AcrB production and having a butanol or 2-butanone biosynthetic pathway are useful for production of butanol or 2-butanone.
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申请公布号 |
US2009162911(A1) |
申请公布日期 |
2009.06.25 |
申请号 |
US20080330531 |
申请日期 |
2008.12.09 |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
LAROSSA ROBERT A.;SMULSKI DANA R. |
分类号 |
C12P7/26;C12N1/21;C12N15/87;C12P7/16 |
主分类号 |
C12P7/26 |
代理机构 |
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代理人 |
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地址 |
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