发明名称 Method useful for amplifying, detecting and depleting pathologic forms of the cellular prion protein
摘要 The present invention relates to a method for selectively amplifying the oligomerization of at least one PrP Sc isoform of the PrP C cellular prion protein, characterized in that it comprises bringing said PrP Sc isoform, under conditions suitable for amplification, together with an effective amount of at least one compound of general formula I as follow: The instant invention is also directed to new compounds of formula I and pharmaceutical compositions including them.
申请公布号 EP2072511(A1) 申请公布日期 2009.06.24
申请号 EP20070124044 申请日期 2007.12.21
申请人 INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) 发明人
分类号 C07D409/04 主分类号 C07D409/04
代理机构 代理人
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