发明名称 |
QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY |
摘要 |
The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors. |
申请公布号 |
KR20090067169(A) |
申请公布日期 |
2009.06.24 |
申请号 |
KR20097007433 |
申请日期 |
2009.04.10 |
申请人 |
CURIS, INC. |
发明人 |
QIAN CHANGGENG;CAI XIONG;GOULD STEPHEN;ZHAI HAIXIAO |
分类号 |
C07D239/88;A61K31/517;A61P35/04;C07D239/93 |
主分类号 |
C07D239/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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